PMM). Garrison-Morton 2403; Grolier Medicine 92; Heirs of Hippocrates 2159; Osler 1697; PMM 402; Waller 2707; Norman 686. [With:] WADD, William. Comments on Corpulency. London, 1829. 8o. Engraved plates. Later cloth. FIRST EDITION. -- PAULING, Linus. The Nature of the Chemical Bond. Ithaca, NY, 1939. 8o. Original cloth; dust jacket. FIRST EDITION. -- PAULING. Vitamin C and the Common Cold. New York, 1971. Soft glazed paper covers. Later edition, PRESENTATION COPY, inscribed by Pauling to Francis O. Schmitt. -- PAULING and Ewan CAMERON. Cancer and Vitamin C. Menlo Park, CA, 1979. Original cloth; dust jacket. FIRST EDITION, SIGNED by the authors. -- FUNK, Casmir. Die Vitamine. Wiesbaden, 1914. 4o. Later half cloth. FIRST EDITION, a pioneering work in the study of vitamins. -- [LIBMAN, Emanuel]. Contributions to the Medical Sciences in Honor of Dr. Emanuel Libman. New York, 1932. 3 volumes, 4o. Original cloth. FIRST EDITION, presentation copy, inscribed by Libman to Jesse Bullowa, a contributor to the publication. -- BANTING, William. Letter on Corpulence Addressed to the Public. London, 1864. 8o. Original printed wrappers. Third edition. Together 11 volumes, condition varies. (10) " /> [MEDICINE]. -- EHRLICH, Paul (1854-1915) and Sahachiro HATA (1873-1938). <I>Die experimentelle Chemotherapie der Spirillosen (Syphilis, Rückfallfieber, Hühnerspirillose, Frambösie)</I>. Berlin: Julius Springer, 1910. 8<V>o (232 x 153 mm). 5 halftone plates, 3 folding printed tables, text diagrams. Original grey cloth, gilt. FIRST EDITION, OF THE FIRST CHAPTER IN THE HISTORY OF CHEMOTHERAPY. Ehrlich had the idea of a "magic bullet" drug -- one that could seek out and attack invading organisms but not affect the host tissue -- after performing experiments with dyes in which bacteria had absorbed a stain while the surrounding micro-organism had not. Ehrlich and his assistant Hata performed 605 experiments with arsenical compounds on the spirochaeta pallida, the organism causing syphilis, which Fritz Schaudinn had identified in 1905, before they succeeded using a compound that they named "Salvarsan 606." "This was the first chapter in the history of chemotherapy, later stages being marked by the discovery of prontosil and the brilliantly successful sulpha drugs, including the well-known 'M. & B. 693' which was to save the life of Winston Churchill at a critical point in the Second World War" (<I>PMM</I>). Garrison-Morton 2403; Grolier <I>Medicine</I> 92; <I>Heirs of Hippocrates</I> 2159; Osler 1697; <I>PMM 402</I>; Waller 2707; Norman 686. [<I>With:</I>] WADD, William. <I>Comments on Corpulency</I>. London, 1829. 8<V>o. Engraved plates. Later cloth. FIRST EDITION. -- PAULING, Linus. <I>The Nature of the Chemical Bond</I>. Ithaca, NY, 1939. 8<V>o. Original cloth; dust jacket. FIRST EDITION. -- PAULING. <I>Vitamin C and the Common Cold</I>. New York, 1971. Soft glazed paper covers. Later edition, PRESENTATION COPY, inscribed by Pauling to Francis O. Schmitt. -- PAULING and Ewan CAMERON. <I>Cancer and Vitamin C</I>. Menlo Park, CA, 1979. Original cloth; dust jacket. FIRST EDITION, SIGNED by the authors. -- FUNK, Casmir. <I>Die Vitamine</I>. Wiesbaden, 1914. 4<V>o. Later half cloth. FIRST EDITION, a pioneering work in the study of vitamins. -- [LIBMAN, Emanuel]. <I>Contributions to the Medical Sciences in Honor of Dr. Emanuel Libman</I>. New York, 1932. 3 volumes, 4<V>o. Original cloth. FIRST EDITION, presentation copy, inscribed by Libman to Jesse Bullowa, a contributor to the publication. -- BANTING, William. <I>Letter on Corpulence Addressed to the Public</I>. London, 1864. 8<V>o. Original printed wrappers. Third edition. Together 11 volumes, condition varies. (10) | Christie's
  • Christies auction house James Christie logo

    Sale 2013

    Important Scientific Books: The Richard Green Library

    17 June 2008, New York, Rockefeller Plaza

  • Lot 247

    [MEDICINE]. -- EHRLICH, Paul (1854-1915) and Sahachiro HATA (1873-1938). Die experimentelle Chemotherapie der Spirillosen (Syphilis, Rückfallfieber, Hühnerspirillose, Frambösie). Berlin: Julius Springer, 1910. 8o (232 x 153 mm). 5 halftone plates, 3 folding printed tables, text diagrams. Original grey cloth, gilt. FIRST EDITION, OF THE FIRST CHAPTER IN THE HISTORY OF CHEMOTHERAPY. Ehrlich had the idea of a "magic bullet" drug -- one that could seek out and attack invading organisms but not affect the host tissue -- after performing experiments with dyes in which bacteria had absorbed a stain while the surrounding micro-organism had not. Ehrlich and his assistant Hata performed 605 experiments with arsenical compounds on the spirochaeta pallida, the organism causing syphilis, which Fritz Schaudinn had identified in 1905, before they succeeded using a compound that they named "Salvarsan 606." "This was the first chapter in the history of chemotherapy, later stages being marked by the discovery of prontosil and the brilliantly successful sulpha drugs, including the well-known 'M. & B. 693' which was to save the life of Winston Churchill at a critical point in the Second World War" (PMM). Garrison-Morton 2403; Grolier Medicine 92; Heirs of Hippocrates 2159; Osler 1697; PMM 402; Waller 2707; Norman 686.

    [With:] WADD, William. Comments on Corpulency. London, 1829. 8o. Engraved plates. Later cloth. FIRST EDITION. -- PAULING, Linus. The Nature of the Chemical Bond. Ithaca, NY, 1939. 8o. Original cloth; dust jacket. FIRST EDITION. -- PAULING. Vitamin C and the Common Cold. New York, 1971. Soft glazed paper covers. Later edition, PRESENTATION COPY, inscribed by Pauling to Francis O. Schmitt. -- PAULING and Ewan CAMERON. Cancer and Vitamin C. Menlo Park, CA, 1979. Original cloth; dust jacket. FIRST EDITION, SIGNED by the authors. -- FUNK, Casmir. Die Vitamine. Wiesbaden, 1914. 4o. Later half cloth. FIRST EDITION, a pioneering work in the study of vitamins. -- [LIBMAN, Emanuel]. Contributions to the Medical Sciences in Honor of Dr. Emanuel Libman. New York, 1932. 3 volumes, 4o. Original cloth. FIRST EDITION, presentation copy, inscribed by Libman to Jesse Bullowa, a contributor to the publication. -- BANTING, William. Letter on Corpulence Addressed to the Public. London, 1864. 8o. Original printed wrappers. Third edition. Together 11 volumes, condition varies. (10)

    Price Realised  

    Estimate

    [MEDICINE]. -- EHRLICH, Paul (1854-1915) and Sahachiro HATA (1873-1938). Die experimentelle Chemotherapie der Spirillosen (Syphilis, Rückfallfieber, Hühnerspirillose, Frambösie). Berlin: Julius Springer, 1910. 8o (232 x 153 mm). 5 halftone plates, 3 folding printed tables, text diagrams. Original grey cloth, gilt. FIRST EDITION, OF THE FIRST CHAPTER IN THE HISTORY OF CHEMOTHERAPY. Ehrlich had the idea of a "magic bullet" drug -- one that could seek out and attack invading organisms but not affect the host tissue -- after performing experiments with dyes in which bacteria had absorbed a stain while the surrounding micro-organism had not. Ehrlich and his assistant Hata performed 605 experiments with arsenical compounds on the spirochaeta pallida, the organism causing syphilis, which Fritz Schaudinn had identified in 1905, before they succeeded using a compound that they named "Salvarsan 606." "This was the first chapter in the history of chemotherapy, later stages being marked by the discovery of prontosil and the brilliantly successful sulpha drugs, including the well-known 'M. & B. 693' which was to save the life of Winston Churchill at a critical point in the Second World War" (PMM). Garrison-Morton 2403; Grolier Medicine 92; Heirs of Hippocrates 2159; Osler 1697; PMM 402; Waller 2707; Norman 686.

    [With:] WADD, William. Comments on Corpulency. London, 1829. 8o. Engraved plates. Later cloth. FIRST EDITION. -- PAULING, Linus. The Nature of the Chemical Bond. Ithaca, NY, 1939. 8o. Original cloth; dust jacket. FIRST EDITION. -- PAULING. Vitamin C and the Common Cold. New York, 1971. Soft glazed paper covers. Later edition, PRESENTATION COPY, inscribed by Pauling to Francis O. Schmitt. -- PAULING and Ewan CAMERON. Cancer and Vitamin C. Menlo Park, CA, 1979. Original cloth; dust jacket. FIRST EDITION, SIGNED by the authors. -- FUNK, Casmir. Die Vitamine. Wiesbaden, 1914. 4o. Later half cloth. FIRST EDITION, a pioneering work in the study of vitamins. -- [LIBMAN, Emanuel]. Contributions to the Medical Sciences in Honor of Dr. Emanuel Libman. New York, 1932. 3 volumes, 4o. Original cloth. FIRST EDITION, presentation copy, inscribed by Libman to Jesse Bullowa, a contributor to the publication. -- BANTING, William. Letter on Corpulence Addressed to the Public. London, 1864. 8o. Original printed wrappers. Third edition. Together 11 volumes, condition varies. (10)


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