Third daughter of the future Paul I and Maria Feodorovna, she displayed a talent for music at an early age. In 1804 she married Carl Friedrich of Saxe-Weimar-Eisenach, who died in 1853. Her life was dedicated to the arts and sciences being hailed by Goethe as one of the worthiest women of her time.
This miniature is copied after Jean-Baptiste Isabey's miniature painted in Vienna in 1815, illustrated in the exhibition catalogue Jean-Baptiste Isabey (1767-1855), portraitiste de l'Europe, Malmaison Castle, and Nancy, Musée des Beaux-Arts, 2005/2006, p. 78, no. 146.