Francis I (1765-1835) Holy Roman Emperor 1792-1806 and Emperor of Austria 1806-1835) in brown coat with gold buttons, white waistcoat and high stock; and his wife, Empress Maria Theresa (1772-1807), in blue dress with white underdress, pearls in her upswept fair hair

Emperor Francis I married his first cousin Maria Theresa, eldest daughter of Ferdinando I, King of the Two Sicilies, as his second wife and had issue.
An almost identical pair in a double-sided locket, also attributed to Guérard, is illustrated in J. Nimmergut/A.-M. Wager, Miniaturen. Dosen, Munich, 1982, no. 166, illustrated p. 171 (with the Empress mis-identified).