JOSEPH, BARON LISTER (1827-1912)
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JOSEPH, BARON LISTER (1827-1912)

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JOSEPH, BARON LISTER (1827-1912)
Autograph manuscript, notes of experimental observations on the transmission of tuberculosis between humans, pigs and calves, n.p. [London], n.d. [1902], the pages cancelled lightly in pencil, perhaps after copying, 5½ pages, 8vo, one leaf on verso of paper with printed heading of 12 Park Crescent, Portland Place.

THE INFECTIOUSNESS OF TUBERCULOSIS. The three leaves are on separate but related aspects of the subject: the first comprises notes of the reactions of pigs and calves to both inoculation and ingestion of tubercular matter; the second is a series of notes from 'Dean's report 29A of 1902', also relating to experiments on calves; the third contains notes towards a more extended argument based on the experimental observations, including a decisive refutation of a thesis of Robert Koch (the German scientist who had discovered the tuberculosis bacillus): 'The fact that pigs can be so readily infected with human tubercle [is] very important hygienically, as indicating the probability that the flesh of tubercular pigs is dangerous to man. Did not Koch say that it was impossible to communicate human tubercle to calves? Our experiments shew that it is not so'.

At the Tuberculosis Congress of 1901, at a session chaired by Lister, Koch had advanced the startling proposition that bovine and human tuberculosis were two separate diseases. Lister had opposed this thesis immediately, and in 1902 proposed, and oversaw, two series of experiments at the British Institute of Preventive Medicine (later the Lister Institute) to test Koch's views: the first series, using pigs as subjects, tested Koch's thesis as to the difference between human and bovine tuberculosis; the second series, using a number of animals, examined whether bovine tuberculosis became more virulent by transmission through other species.
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