A sample of penicillium mould presented by Alexander Fleming,

Details
A sample of penicillium mould presented by Alexander Fleming,
mounted in a glazed wooden box, with brass front plate inscribed PENICILLIUM MOULD FROM PROFESSOR ALEXANDER FLEMING 1935, the back with manuscript vellum label THIS SAMPLE OF PENICILLIUM MOULD WAS GIVEN TO DOUGLAS MACLEOD BY SIR ALEXANDER FLEMING IN 1935 in leather covered border -- 3in. (7.6cm.) wide; a framed and glazed monochrome portrait photograph of Fleming in his laboratory, with manuscript ink inscription With kind regards to the hielander Alexander Fleming -- 8in. (20.5cm.) high; and a bronze medal and stand, the obverse signed R.B. BARON with inscription ALEXANDER FLEMING PRIX NOBEL 1945, showing Fleming in profile, the reverse depicting a microscope and penicillium mould, with inscription DECOUVERTE DE LA PENICILLINE -- 2¾in. (7cm.) diameter

See Colour Illustration and Details (3)
Provenance
Presented to Douglas Macleod, and thence by direct descent.
Literature
André Maurois The Life of Sir Alexander Fleming (London, 1959)
Dictionary of Scientific Biography (New York, 1970-80). Fleming, Alexander.
British Medical Journal (London, 7 February 1970). Obituary of Douglas MacLeod, p. 370.

Lot Essay

Douglas Hamilton MacLeod M.S. Lond., F.R.C.P., F.R.C.S., F.R.C.O.G. was appointed to the staff of St. Mary's Hospital in 1935, where Fleming had studied, and been working since qualifying in 1906. It was at St. Mary's that Fleming had discovered the antibacterial properties of penicillium mould in 1928, and that he presented this sample of mould to MacLeod, whom he knew by the nickname "the hielander" (i.e. highlander).
Maurois, in his biography of Fleming, quotes MacLeod's recollection of the presentation: "I asked him what the substance was called. He said that he had given it the name 'penicillin'. I had to admit that I had never heard of it. He asked me to go with him to his laboratory, which I did. He showed me the mould, and actually gave me a specimen, which I still have". Maurois dates this meeting to 1936, whereas the case is marked "1935". However the mould sample was mounted some years later by MacLeod's wife, who must have misremembered the date.
Fleming was made Professor of Bacteriology, University of London in 1928, and awarded the Nobel Prize in medicine in 1945 with Ernst Chain and Howard Florey.

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