HARRISON, ANNA, S., First Lady. Autograph letter signed ("Anna Harrison") to William H. Birkham, Northbend, Ohio, 19 September 1850. 1 page, 4to, one tiny tear to left margin, otherwise in very good condition. The former First Lady supplies an early collector with her late husband's signature: "I hasten to send you an Autograph of my dear departed Husband, altho, I am now oblig'd to cut them from letters, & Books, but I always feel anxious to comply with every request if I can..." -- WILLIAM HENRY HARRISON, President. Signature, clipped by Anna Harrison and sent with the preceding, tipped to lower blank margin of the letter.