A fine trepanning set signed COTZANI with ebony handles, steel and brass instruments, two trephines (23mm.) and (16mm)diam.,drill stock with fluted ebony handle, a dura cutter with fluted handle and turned finial, baluster shaped grip gull winged elevators, a button shaped elevator, an arrowhead perforator, skull saw with adjustable blades, and a brush in fitted velvet and silk interior in walnut case with brass fittings c.1750