SCALIGER, Julius Caesar (1484-1558). Exotericarum exercitationum liber quintus decimus, De subtilitate ad Hieronymum Cardanum, Paris: Michel Vascosan, 1557. 4° (230 x 158mm). A few woodcut illustrations and diagrams, with the final blank, quire ZZ duplicated. (A few quires in the middle spotted.) Contemporary vellum (lacks ties). Provenance: Nicolas Bergier, advocat at Reims (early 17th-century signature) -- deleted ownership inscription of a Jesuit college, dated 1660, on title. FIRST EDITION of Scaliger's treatise on natural science which included an important critique of Cardano's De Subtilitate (1550). Adams S579.