LOCKE, John (1632-1704). An Essay concerning Humane Understanding, London: for A. and J. Churchill, 1700. 2° (302 x 195mm). Engraved portrait by Vanderbanck after Brunower, signature Gg a single sheet. (A few inkspots on title, contents generally lightly browned and spotted.) Early 18th-century half calf (short split in upper hinge, lightly rubbed, corners worn). Provenance: John Ducane (contemporary signature on recto of portrait) -- Richard Humfrey (with inscription under the above 'ex dono H. Du Cane, April 30. 1769') -- Elisa Maltby (signature dated 1780). Fourth edition. 'Locke was the first to take up the challenge of Bacon and to attempt critically the certainty and the adequacy of human knowledge when confronted with God and the Universe...', PMM 164; Wing L2742.