1943: LSD is synthesized for the first time by Swiss scientist Albert Hoffman.

LSD was the 'drug-de-jour' in the 1960s and played a major role in the counter-culture movement of the decade. Very little was known about the drug at first, a point that the exploitation industry was quick to seize upon, capitalizing on the widespread ignorance to sell films like Hallucination Generation and The Weird World Of LSD. The latter was strikingly reminiscent of 1930s drug menace films, the main difference being the substitution of LSD for marijuana.