This beautiful, unfinished plate is a rare example of a French Pestblatt, a broadside depicting a saint or saints venerated for their healing powers, and it was very likely made during an outbreak of the Plague in Burgundy in 1554. It displays a strong Italianate influence, with the finely modeled figure of Saint Sebastian in particular being directly inspired by Mantegna's engraving of The Risen Christ between Saint Andrew and Saint Longinus (B. 6). However, Duvet's treatment is characteristically idiosyncratic. The perspective is distorted and flattened, and the saints, angels, animals, and tree are dynamically connected by flowing robes, wings, limbs and fur - all animated by the sketch-like quality of Duvet's line.
It can be assumed that Duvet's plates were printed in small numbers only - certainly few survive to this day. The present work is thought to have been printed in two editions, with and without text. The only known impression with text was destroyed in Dresden in World War II. Eisler records fifteen impressions without text in public collections.