The sitter was the son of Sir James Rushout, 1st Bt., of Milnst-Maylards, Essex, and succeeded his nephew Sir James Rushout, in 1711. He was Member of Parliament for Malmesbury (elected 1713 and again in 1715), then for Malmesbury and Evesham (elected in 1722), and continued to represent Evesham, having been unseated in Malmesbury, until he retired from parliament in 1768. In the House of Commons he spoke freqeuntly against the measures of Sir Robert Walpole and was one of the committee put together to investigate Walpole's conduct in 1742. He held the lucrative office of Treasurer to the Navy in 1743 and was appointed a member of the Privy Council in the following year. He married Lady Anne, Daughter of George Compton, 4th Earl of Northampton, and was succeeded by his only son John, of Northwick Park, Worcestershire, who was created 1st Baron Northwick.