Lord George was the third son of Lionel Cranfield Sackville, 7th Earl and 1st Duke of Dorset. He was educated at Westminster School and Trinity College Dublin. He entered the army in April 1737 and was Lieutenant Colonel of the 28th Regiment of Foot by 1740. A distinguished military figure, Lord George succeeded Marlborough as Commander in Chief of the British forces in the Rhine after his death from the epidemic which had swept therough the army. He therefore came under the command of Prince Ferdinand of Brunswick with whom he soon quarrelled. At the Battle of Minden imprecise instructions from the Prince for the cavalry to advance and subsequent disgreements resulted in Sackville being omitted from the report of the battle and being dismissed from the army on his return to London. Sackville pressed for his own court marshall in an attempt to clear his name, however, when his wish was granted, he was found guilt of disobeying orders and was judged 'unfit to serve his majesty in any military capacity whatever'. The sentance was confirmed by the King, George II, and Sackville was removed from the Privy Council. After the death of the King there was reaction against the harshness of the sentance. Despite loosing his commission and his position as a Privy Councillor he remained a Member of Parliament. First returned as one of the Members of Parliment for Dover, he sat for the borough until 1761 when he was returned for East Grinstead and Hythe and it was as M.P. for these towns that he spoke in Parliament after his disgrace. By 1763 Lord Bute was writing to Sir Harry Erskine and admitting that the new King, George III, felt Sackville had be harsly treated. Soon he was re-appointed to the Privy Council and received at court. His public reputation was enchanced by a duel he fought with Captain George Johnston M.P., in Hyde Park in December 1770. Both men were unscathed, Johnston declaring afterwards that 'he never knew a man behave better than Germain.' Sackville had taken the name Germain instead of Sackville in accordance with the will if Lady Betty Germain in 1770. Further evidence of his re-acceptance was his appointment as a lord commissioner of trade and plantations and secretary of state for the colonies by Lord North in 1775. Moreover, on the fall of the North ministry he was created Viscount Sackville of Drayton Manor, Northamptonshire and Baron Bolebroke of Sussex. He died at Stoneland Lodge, his house in Sussex, in 1785.