Lot 474
474
GRAAF, Regnier de (1641-1673). De succi pancreatici natura et usu exercitatio anatomico-medica. Leiden: Hack, 1664.
GRAAF, Regnier de (1641-1673). De succi pancreatici natura et usu exercitatio anatomico-medica. Leiden: Hack, 1664.

Details
GRAAF, Regnier de (1641-1673). De succi pancreatici natura et usu exercitatio anatomico-medica. Leiden: Hack, 1664.

12o (128 x 72 mm). Woodcut title-vignette. 3 folding engraved plates (one torn slightly at fold). (Some minor brown spotting.) Contemporary vellum. Provenance: Rudolf Virchow (1821-1902), German pathologist and author of Die Cellularpathologie, published in 1858 (bookplate with his famous motto: "omnis cellula a cellula").

VIRCHOW'S COPY OF THE EXCEEDINGLY RARE FIRST EDITION of Graaf's important study on pancreatic secretion. His experiments, performed when he was 22, are among the earliest investigations of the physiology of the pancreas. "He collected the pancreatic juice of dogs by means of artificial pancreatic fistulae, commenting on the small quantitiy of juice secreted and on its alkaline character" (Garrison-Morton). Garrison-Morton 974; Norman 923.

[Bound with:]

SENGUERDIUS, Wolferdus (1646-1724). Tractatus physicus de tarantula. -Oratio inauguralis de usu et dignitate philosophiae. Leiden: Gaasbeeck, 1668. 12o. Engraved frontispiece. NLM/Krivatsy 10902. -- Gyrgy KOVCS, tatai (b. 1645). Hercules vere cognitus, certus exul, id est epilepsiae vera dignotio, ac ejusdem certa curatio. Leyden: Arnold Doude, 1670. 12o. (Lacks plate.) NLM/Krivatsy 6489 ("plate wanting"); Wellcome III, p. 411. -- Marcello MALPIGHI (1628-1694). De viscerum structura exercitatio anatomica. Amsterdam: Peter le Grand, 1669. 12o. NLM/Krivatsy 7333. -- Charles DRELINCOURT (1633-1697). Quaestio medica de partu octimestri vivaci. Leiden: Felice Lopez de Haro, 1668. 12o. NLM/Krivatsy 3381.